Diversity, Genome, and Microorganisms - insects interactions (DGIMI)

- Epigenetics, holocentrism and adaptation of insects;

- Functional genomes and virulent bacterial factors;

- Dynamics of densovirus interactions in insects;

- Biological and genetic resources of bacteria and entomopathogenic nematodes;

- Integrative biology of host-parasitoid interactions.

- QIPBCA (Quarantine Insect Platform for Biological Control Assays)

- SPODOBASE (one of the largest EST databases for a noctuid that is available to the whole scientific community)

- A high quality BAC resource (average insert size of 125 kb, coverage of 10X) made for a noctuid

- An insectarium complying with NS2 standards

2005 à 2009: 79

1. Provost B, Jouan V, Hilliou F, Delobel P, Bernardo P, Ravallec M, Cousserans F, Wajnberg E, Darboux I, Fournier P, Strand MR, Volkoff AN. 2011. Lepidopteran transcriptome analysis following infection by phylogenetically unrelated polydnaviruses highlights differential and common responses. Insect Biochem Mol Biol. 41:582-91.

2. Aymeric JL, Givaudan A, Duvic B. Imd pathway is involved in the interaction of Drosophila melanogaster with the entomopathogenic bacteria, Xenorhabdus nematophila and Photorhabdus luminescens. Mol Immunol. 2010. 47:2342-8. Epub 2010 Jun 2. PubMed PMID: 20627393.

3. Costa SC, Varela Chavez C, Jubelin G, Givaudan A, Escoubas JM, Brehélin M, Zumbihl R. Recent insight into the pathogenicity mechanisms of the emergent pathogen Photorhabdus asymbiotica. Microbes Infect. 2010. 12:182-9.

4. d'Alençon E, Sezutsu H, Legeai F, Permal E, Bernard-Samain S, Gimenez S, Gagneur C, Cousserans F, Shimomura M, Brun-Barale A, Flutre T, Couloux A, East P, Gordon K, Mita K, Quesneville H, Fournier P, Feyereisen R. Extensive synteny conservation of holocentric chromosomes in Lepidoptera despite high rates of local genome rearrangements. Proc Natl Acad Sci U S A. 2010. 107:7680-5.

5. Mutuel D, Ravallec M, Chabi B, Multeau C, Salmon JM, Fournier P, Ogliastro M. Pathogenesis of Junonia coenia densovirus in Spodoptera frugiperda: a route of infection that leads to hypoxia. Virology. 2010. 403:137-44.

6. Ogier JC, Calteau A, Forst S, Goodrich-Blair H, Roche D, Rouy Z, Suen G, Zumbihl R, Givaudan A, Tailliez P, Medigue C, Gaudriault S. Units of plasticity in bacterial genomes: new insight from the comparative genomics of two bacteria interacting with invertebrates, Photorhabdus and Xenorhabdus. BMC Genomics. 2010. 11:568. [Epub ahead of print] PubMed PMID: 20950463.

7. Tailliez P, Laroui C, Ginibre N, Paule A, Pagès S, Boemare N. Phylogeny of Photorhabdus and Xenorhabdus based on universally conserved protein-coding sequences and implications for the taxonomy of these two genera. Proposal of new taxa: X. vietnamensis sp. nov., P. luminescens subsp. caribbeanensis subsp. nov., P. luminescens subsp. hainanensis subsp. nov., P. temperata subsp. khanii subsp. nov., P. temperata subsp. tasmaniensis subsp. nov., and the reclassification of P. luminescens subsp. thracensis as P. temperata subsp. thracensis comb. nov. Int J Syst Evol Microbiol. 2010. 60:1921-37.

8. Varela Chavez C, Jubelin G, Courties G, Gomard A, Ginibre N, Pages S, Taïeb F, Girard PA, Oswald E, Givaudan A, Zumbihl R, Escoubas JM. The cyclomodulin Cif of Photorhabdus luminescens inhibits insect cell proliferation and triggers host cell death by apoptosis. Microbes Infect. 2010. Sep 24. [Epub ahead of print] PubMed PMID: 20870031.

9. Volkoff AN, Jouan V, Urbach S, Samain S, Bergoin M, Wincker P, Demettre E, Cousserans F, Provost B, Coulibaly F, Legeai F, Béliveau C, Cusson M, Gyapay G, Drezen JM. Analysis of virion structural components reveals vestiges of the ancestral ichnovirus genome. PLoS Pathog. 2010. 6:e1000923. PubMed PMID:20523890; PubMed Central PMCID: PMC2877734.

10. Abi Khattar Z, Rejasse A, Destoumieux-Garzón D, Escoubas JM, Sanchis V, Lereclus D, Givaudan A, Kallassy M, Nielsen-Leroux C, Gaudriault S. The dlt operon of Bacillus cereus is required for resistance to cationic antimicrobial peptides and for virulence in insects. J Bacteriol. 2009. 191:7063-73.

11. Bézier A, Annaheim M, Herbinière J, Wetterwald C, Gyapay G, Bernard-Samain S, Wincker P, Roditi I, Heller M, Belghazi M, Pfister-Wilhem R, Periquet G, Dupuy C, Huguet E, Volkoff AN, Lanzrein B, Drezen JM. Polydnaviruses of braconid wasps derive from an ancestral nudivirus. Science. 2009. 323:926-30.

12. Destoumieux-Garzon D, Brehelin M, Bulet P, Boublik Y, Girard PA, Baghdiguian S, Zumbihl R, Escoubas JM. Spodoptera frugiperda X-tox protein, an immune related defensin rosary, has lost the function of ancestral defensins. PloS One. 2009. 4(8), e6795.

13. Jubelin G, Varela Chavez C, Taieb F, Banfield MJ, Samba-Louaka A, Nobe R, Nougayrède JP, Zumbihl R, Givaudan A, Escoubas JM, Oswald E. Cycle inhibiting factors (CIFs)are a growing family of functional cyclomodulins present in invertebrate and mammal bacterial pathogens. PLoS One. 2009. 4(3):e4855.

14. Serbielle C, Moreau S, Veillard F, Voldoire E, Bézier A, Mannucci MA, Volkoff AN, Drezen JM, Lalmanach G, Huguet E. Identification of parasite-responsive cysteine proteases in Manduca sexta. Biol Chem. 2009. 390:493-502.

15. Vendeville A, Ravallec M, Jousset FX, Devise M, Mutuel D, López-Ferber M, Fournier P, Dupressoir T, Ogliastro M. Densovirus infectious pathway requires clathrin-mediated endocytosis followed by trafficking to the nucleus. J Virol. 2009. 83:4678-89.