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Integrative Modelling for understanding GenesxEnvironmentxProcesses interactions in the determinims of fruit and leaf growth

  • Agricultural system


The project aims to measure cell division, cell expansion and DNA endoreduplication during leaf and fruit development in order to develop a model capable of predicting the interactions between these processes in response to water supply.


The aim is (1) to develop a conceptual model of the interactions between cell division, cell expansion and endoreduplication in growing leaves and fruit; (2) to quantify and analyse the contribution of each of these processes to the response of the organ to water stress; (3) to integrate the knowledge into a mechanistic model that will make it possible to carry out in silico experiments and test the hypotheses put forward. The work focuses on WVA 106 and on transgenic mutants affected on the growth processes.


Within a leaf, cellular characteristics are common to all leaflets. At the plant scale variations in leaf or leaflet size are related to variations in the number of epidermal cells (Koch et al. 2018).
- DH reduces the size/mass of all organs. The reduction in leaf area is primarily related to a reduction in cell number, with small effects on cell size and endoreduplication levels. In fruit, the effect of DH is more marked on expansion than on cell division or endoreduplication.
- A first fruit model coupling growth processes has been developed (Baldazzi et al. submitted). Its validation under different DH conditions (in progress) is a key step towards improving the manipulation of organ size and quality, evaluating existing genotypes and developing varieties adapted to the new agricultural context.

  • Project Number
  • Call for project
  • Start date :
    1 March 2015
  • Closing date :
    31 March 2018
  • Flagship project :
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